Posts from Norway
An extended and improved CCF for the mouse brain has been added to BrainGlobe
- 06 June 2025
Piluso et al., 2025 recently published an extended and improved Common Coordinate Framework atlas version of the entire mouse brain, called CCFv3BBP or CCFv3a extended. While the previous CCFv2 and CCFv3 atlas versions from the Allen Institute for Brain Science (AIBS) have been widely adopted by the neuroscience community, they retained certain limitations. The updated framework addresses these by incorporating the most rostral and caudal parts of the brain, resulting in a non-truncated main olfactory bulb, cerebellum, and medulla (CCFv3a), features absent or truncated in earlier versions. Additionally, the cerebellum annotation now includes the granular, molecular, and Purkinje cell layers. This new version incorporates a high resolution (10 µm isotropic) Nissl-stained volume precisely aligned to the CCFv3a.
An Atlas for the non-human primate Microcebus murinus (grey mouse lemur) has been added to BrainGlobe
- 28 January 2025
Thanks to its small size and its close phylogenetic relation to humans (compared to other model organisms), the grey mouse lemur is a practical choice to study brain evolution and disease. Nadkarni et al. made the first publicly available mouse lemur atlas in 2018. They imaged mouse lemur brains with MRI at 91μm resolution. Thanks to Harry Carey (University of Oslo) it is now accessible from BrainGlobe. In reference to its original authors, the atlas is named nadkarni_mri_mouselemur_91um in the BrainGlobe ecosystem.